In our lecture we explore the fascinating world of bacteria, antibiotics and antibiotic resistance. Together we discover what challenges society is facing due to increasing resistances. We will take a look behind the scenes of a microbiology laboratory and introduce you to our Institute of Medical Microbiology at the University of Zurich. You will learn about the contribution of the interdisciplinary team of clinical microbiologists, biomedical analysts and researchers to the fight against antibiotic resistance.